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The investigation on daily sequential PCR testing of the quarantined subjects indicated the viral load of the first positive test of Delta infections was ~1000 times higher than that of the 19A/19B strains infections back in the initial epidemic wave of 2020, suggesting the potential faster viral replication rate and more infectiousness of the Delta variant at the early stage of the infection. All 167 infections could be traced back to the first index case. We report the first local transmission of the Delta SARS-CoV-2 variant in mainland China. Corresponding authors: Yan Li, Jun Yuan, Jianfeng He, Jing Lu.Lythgoe6, Yan Li1,2*, Jun Yuan3*, Jianfeng He1,2*, Jing Lu1,2,4*ġGuangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong, ChinaĢGuangdong Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of Medical Sciences, Guangzhou, Guangdong, ChinaģGuangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, ChinaĤGuangdong Provincial Institution of Public Health, Guangzhou, Guangdong, ChinaĥDepartment of Zoology, University of Oxford, Oxford OX1 3SZ, UKĦBig Data Institute, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7LF, UK
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Viral infection and transmission in a large well-traced outbreak caused by the Delta SARS-CoV-2 variantīaisheng Li1,2#, Aiping Deng1,2#, Kuibiao Li3#, Yao Hu1,2#, Zhencui Li1,2#, Qianling Xiong1,2,4, Zhe Liu1,2, Qianfang Guo1,2, Lirong Zou1,2, Huan Zhang1,2,Meng Zhang1,2, Fangzhu Ouyang1,2, Juan Su1,2, Wenzhe Su3, Jing Xu1,2, Huifang Lin1,2,4, Jing Sun1,2,4, Jingju Peng1,2,4, Huiming Jiang1,2,4, Pingping Zhou1,2,4, Huanying Zhen1,2, Jianpeng Xiao1,2,4, Tao Liu1,2,4, Rongfei Che1,2, Hanri Zeng1,2, Zhonghua Zheng1,2, Yushi Huang1,2, Jianxiang Yu1,2, Lina Yi1,2,4, Jie Wu1,2, Jingdiao Chen1,2, Haojie Zhong1,2, Xiaoling Deng1,2, Min Kang1,2, Oliver G.